| Top 20 Ghana Music Video Countdown brought to you by Ghana Music. |
| Week #38 Ending September 25th, 2021. | P | W | L | |
| 1. | Je M’appelle by Darkovibes ft. Davido | 1 | 1 | – |
| 2. | Coachella by Sarkodie ft. Kwesi Arthur | 1 | 17 | 1 |
| 3. | Second Sermon by Black Sherif | 2 | 10 | 2 |
| 4. | Heat by Wendy Shay ft. Shay Gang | 3 | 3 | 3 |
| 5. | Need Me by Gyakie | 4 | 6 | 5 |
| 6. | Eka Aba Fie by Opanka ft. Shatta Wale | 2 | 7 | 6 |
| 7. | Oldman’s Radio by Samini | 7 | 4 | 8 |
| 8. | Hmmm Chale by Shatta Wale ft. Ara-B | 7 | 3 | 7 |
| 9. | Nampa by Pappy Kojo ft. Magnom & Kelvyn Boy | 4 | 6 | 4 |
| 10. | Awurade Ye by Diana Hamilton | 10 | 2 | 20 |
| 11. | Nhyira by Strongman ft. Akwaboah | 4 | 6 | 9 |
| 12. | Shuperu by Mr Drew ft. KiDi | 12 | 3 | 12 |
| 13. | Aketesia by Kweku Darlington ft. Laycon & Medikal | 7 | 7 | 10 |
| 14. | Yenkyi Bibia by Danno1 ft. Kofi Kinaata | 14 | 4 | 14 |
| 15. | Ring My Line by King Promise ft. Headie One | 13 | 6 | 13 |
| 16. | Attack by Kweku Flick ft. Strongman | 16 | 1 | – |
| 17. | OK by Nautyca ft. Michy | 17 | 1 | – |
| 18. | Keep Moving by Miss A Jay ft. Ayesem | 15 | 4 | 15 |
| 19. | Kiss And Tell by D-Black ft. Akwaboah | 19 | 1 | – |
| 20. | Nipa Bone by Bosom P-Yung | 20 | 1 | – |
| P = Peaked | W = Weeks on Chart | L = Last Week’s Position |
| #top20GHMusicVideos Compiled every week by Ghana Music. |
